Selected Publications
Schwerpunkt Herz-Kreislauf
Merz, S.F., S. Korste, L. Bornemann, L. Michel, P. Stock, A. Squire, C. Soun, D.R. Engel, J. Detzer, H. Lörchner, D. M. Hermann, M. Kamler, J. Klode, Ulrike. B. Hendgen-Cotta, T. Rassaf, M. Gunzer, M. Totzeck (2019): Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and response. Nat Commun. 10(1):2312. doi: 10.1038/s41467-019-10338-2.
Heusch, G. (2020): Myocardial ischaemia-reperfusion injury and cardioprotection in perspective. Nat Rev Cardiol 17(12):773–789. doi: 10.1038/s41569-020-0403-y. Epub 2020 Jul 3.
Schwerpunkt Onkologie
Liu, D., B. Schilling, D. Liu, A. Sucker, E. Livingstone, L. Jerby-Amon, L. Zimmer, R. Gutzmer, I. Satzger, C. Loquai, S. Grabbe, N. Vokes, C.A. Margolis, J. Conway, M.X. He, H. Elmarakeby, F. Dietlein, D. Miao, A. Tracy, H. Gogas, S.M. Goldinger, J. Utikal, C.U. Blank, R. Rauschenberg, D. von Bubnoff, A. Krackhardt, B. Weide, S. Haferkamp, F. Kiecker, B. Izar, L. Garraway, A. Regev, K. Flaherty, A. Paschen, E.M. Van Allen, D. Schadendorf (2019): Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma. Nat Med. 25(12), 1916–1927.
Schuler, M., B.C. Cho, C.M. Sayehli, A. Navarro, R.A. Soo, H. Richly, P.A. Cassier, D. Tai, N. Penel, L. Nogova, S.H. Park, M. Schostak, P.Gajate, R. Cathomas, P. Rajagopalan, J. Grevel, S. Bender, O. Boix, H. Nogai, M. Ocker, P. Ellinghaus, M. Joerger (2019): Rogaratinib in patients with advanced cancers selected by FGFR mRNA expression: a phase 1 dose-escalation and dose-expansion study. Lancet Oncol. 20(10), 1454–1466.
Schwerpunkt Translationale Neuro- und Verhaltenswissenschaften
Masuda, T., R. Sankowski, O. Staszewski, C. Böttcher, L. Amann, Sagar, C. Scheiwe, S. Nessler, P. Kunz, G. van Loo, V.A. Coenen, P.C. Reinacher, A. Michel, U. Sure, R. Gold, D. Grün, J. Priller, C. Stadelmann, M. Prinz (2019): Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution. Nature 56, 388–392.
Hagenacker, T., C.D. Wurster, R. Günther, O. Schreiber-Katz, A. Osmanovic, S. Petri, M. Weiler, A. Ziegler, J. Kuttler, J.C. Koch, I. Schneider, G. Wunderlich, N. Schloss, H.C. Lehmann, I. Cordts, M. Deschauer, P. Lingor, C. Kamm, B. Stolte, L. Pietruck, A. Totzeck, K. Kizina, C. Mönninghoff, O. von Velsen, C. Ose, H. Reichmann, M. Forsting, A. Pechmann, J. Kirschner, A.C. Ludolph, A. Hermann, C. Kleinschnitz (2020): Nusinersen in adults with 5q spinal muscular atrophy: a non-interventional, multicentre, observational cohort study. Lancet Neurol. 19, 317–325.
Schwerpunkt Infektiologie und Immunologie
Lang, J., P. Bohn, H. Bhat, H. Jastrow, B. Walkenfort, F. Cansiz, J. Fink, M. Bauer, D. Olszewski, A.Ramos-Nascimento, V. Duhan, S.K. Friedrich, K.A. Becker, A. Krawczyk, M.J. Edwards, A. Burchert, M. Huber, J. Friebus-Kardash, J.R. Göthert, C. Hardt, H.C. Probst, F. Schumacher, K. Köhrer, B. Kleuser, E.B. Babiychuk, B. Sodeik, J. Seibel, U.F. Greber, P.A. Lang, E. Gulbins, K.S. Lang, J. Lang et al. (2020): Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease. Nat Commun. 11(1):1338.
Grüneboom, A., I. Hawwari, D. Weidner, S. Culemann, S. Müller, S. Henneberg, A. Brenzel, S. Merz, L. Bornemann, K. Zec, M. Wuelling, L. Kling, M. Hasenberg, S. Voortmann, S. Lang, W. Baum, A. Ohs, O. Kraff, H.H. Quick, M. Jäger, S. Landgraeber, M.Dudda, R. Danuser, J.V. Stein, M. Rohde, K. Gelse, A.I. Garbe, A. Adamczyk, A.M. Westendorf, D. Hoffmann, S. Christiansen, D.R. Engel, A. Vortkamp, G. Krönke, M. Herrmann, T. Kamradt, G. Schett, A. Hasenberg, M. Gunzer (2019): A network of trans-cortical capillaries as mainstay for blood circulation in long bones. Nat Metab. 1(2), 236–250.
Schwerpunkt Transplantation
Minor, T., C. von Horn, A. Gallinat, M. Kaths, A. Kribben, J. Treckmann, A. Paul (2020): First-in-man controlled rewarming and normothermic perfusion with cell-free solution of a kidney prior to transplantation, Am J Transplant. 20(4): 1192–1195.
Radtke, S., A. Görgens, S. Vitoriano da Conceição Castro, L. Kordelas, A. Köninger, J. Dürig, M. Möllmann, P.A. Horn, B. Giebel (2019): Human multipotent hematopoietic progenitor cell expansion is neither supported in endothelial and endothelial/mesenchymal co-cultures nor in NSG mice. Science Reports. 9(1): 12914.